Department of Medicine Faculty Profile

Steven White
Section of Pulmonary / Critical Care
Professor of Medicine

e-mail: swhite@medicine.bsd.uchicago.edu
Referring Physician Access Line: 1-877-DOM-2730

Training:

Degree	Year	Institution	Area
BA	1977	Walsh College	Biology
MD	1981	University of Illinois
Residency	1984	Medical College of Virginia	Internal Medicine
Fellowship	1986	The University of Chicago	Pulmonary and Critical Care

Academic Interests:

Dr. White’s interests include the repair and survival of airway epithelium in asthma and airway inflammation. He examines the role of cytokines and corticosteroids in programmed cell death, cell-matrix interactions in cell migration, and the expression of adhesion receptors. Recent areas of emphasis include the role of the actin cytoskeleton as a modulator of early events in apoptosis and the role of transforming growth factor beta as a regulator of airway epithelial cell survival.

Clinical Interests:

Asthma, sarcoidosis and cardiopulmonary exercise testing.

Representative Publications:

White SR, KR Wojcik, DC Gruenert, DR Dorscheid, S Sun. Airway epithelial cell wound repair mediated by alpha-dystroglycan. Am J Respir Cell Mol Biol 24:179-186, 2001.
Dorscheid DR, E Low, A Conforti, S Shifrin, AI Sperling, SR White. Corticosteroid-induced apoptosis in mouse airway epithelium: effect in normal airways and after allergen-induced airway inflammation. J Allergy Clin Immunol 111:360-366, 2003
Tse R, BA Marroquin, DR Dorscheid, SR White. Beta-adrenergic agonists reverse corticosteroid-induced apoptosis of airway epithelial cells. Am J Physiol (Lung Cell Molec Physiol) 285:L393-L404, 2003.
Moore M, BA Marroquin, W Gugliotta, SR White. Rho kinase (ROCK-II) inhibition disrupts the actin cytoskeleton and initiates apoptosis in human airway epithelial cells. Am J Respir Cell Mol Biol 30:379-384, 2004.
Undevia N, DR Dorscheid, BA Marroquin, WL Gugliotta, R Tse, SR White. TGF-â mediated rescue of human airway epithelial cell apoptosis induced by Fas activation or corticosteroids. Am J Physiol (Lung Cell Molec Physiol) 287:L515-L524, 2004