George Bakris
Section of Endocrinology, Diabetes and Metabolism
Professor of Medicine
Director, ASH Comprehensive Hypertension Center
Referring Physician Access Line: 1-877-DOM-2730

Training

DegreeYearInstitutionArea
BA1974The University of ChicagoBiology and Psychology
MA1975The University of ChicagoHuman Development
MD1981University Health Sciences/Chicago Medical SchoolMedicine
Residency1982Mayo Graduate School of MedicineInternal Medicine
Residency1983Washington University School of MedicinePsychiatry
Fellowship1984Mayo Graduate School of MedicinePhysiology and Hypertension
Residency1986University of Illinois at ChicagoInternal Medicine
Fellowship1987The University of ChicagoClinical Pharmacology
Fellowship1988The University of ChicagoNephrology

Academic Interests

Dr. Bakris' academic interests are focused on understanding ethnic disparities in kidney disease development and progression. His specific area of interest involves the interaction of hypertension in the presence and absence of diabetes on development of kidney disease. Blacks have a much higher rate of kidney disease than other ethnic groups. Dr. Bakris' tried to understand why this difference in kidney disease prevalence exists by designing clinical trials. To that end he was one of the Principal Investigators of the NIH funded African American Study of Kidney Disease (AASK) trial completed in 2008. Additionally, he was Co-Principal Investigator of one the research groups funded through a SCOR mechanism to identify specific genes that may account for such disparities. More recently, he served on the excutive committee of the ACCOMPLISH trial which resulted in a paradigm shift of blood pressure treatment guidelines. He is currently the Co-Principal Investigator of the Simplicity HTN-3 trial that focuses on a new technique for controlling refractory hypertension by denervating arteries that feed the kidneys.


Clinical Interests

Teaching clinical research methodology


Representative Publications

  1. Bakris GL, Williams M, Dworkin L, Elliott WJ, Epstein M, Toto R, Tuttle K, Douglas J, Hsueh W, Sowers J for the National Kidney Foundation Hypertension and diabetes Executive Committees Working Group. Preserving renal function in adults with hypertension and diabetes: A Consensus Approach. Am J Kidney Dis 2000;36: 646-661
  2. Wright, JT Jr., Bakris G, Greene T, Agodoa LY, Appel LJ, Charleston J, Cheek D, Douglas-Baltimore JG, Gassman J, Glassock R, Hebert, Jamerson K, Lewis J, Phillips RA, Toto RD, Middleton JT, and Rostand SG. Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. JAMA 2002; 288; 2421-2431
  3. Chobanian, AV, Bakris, GL, Black, HR, Cushman, WC, Green, LA, Izzo,JL Jr., Jones, DW, Materson, BJ, Oparil, S, Wright, JT Jr., and Roccella, EJ. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 Report. JAMA 2003;289:2560-2571
  4. Bakris GL, Sarafidis PA, Weir MR, Dahlöf B, Pitt B, Jamerson K, Velazquez EJ, Staikos-Byrne L,Kelly RY, Shi V, Chiang YT, Weber MA, for the ACCOMPLISH investigators. Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a pre-specified secondary analysis of a randomised controlled trial. Lancet 2010; 375:1173-1181
  5. Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Kirkman MS, Lernmark A, Metzger BE, and Nathan DM. Position statement executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Diabetes Care 2011;34 (6):1419-1423



More Information

For more information about Dr. George Bakris publications and research collaborations , please click here